Ribosomal protein S19



Ribosomal protein S19 (RPS19) is one of the 22 proteins which belong to the small subunit of the bacterial ribosome. It forms a complex with RPS13 that binds to 16S RRNA. The images at the left and at the right correspond to one representative RPS19, i.e. the crystal structure of Ribosomal protein S19 from Thermus thermophilus (2zm6, chain S).

3D Structures of Ribosomal protein S19
Update June 2011

S19
2v7f – RPS19 – Pyroccocus abyssi

1qkh, 1qkf - TtRPS19 - Thermus thermophilus – NMR

S19 in small ribosomal subunit
2zm6, 1n36, 1j5e, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4, 3oto - TtRPS19 in 30S ribosomal subunit+THX+16S RRNA - Thermus thermophilus

2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub, 3pyn, 3pyq, 3pys, 3pyu - TtRPS19 in 30S ribosomal subunit+16S RRNA+RNA fragment

3kc4 – EcRPS19 in 30S ribosomal subunit – Escherichia coli

3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx, 3ofa, 3ofb, 3ofx, 3ofy, 3ofo, 3ofp, 3or9, 3ora, 3oaq, 3oar - EcRPS19 in 30S ribosomal subunit+16S RRNA

1i94, 1fka - TtRPS19 in 30S ribosomal subunit+16S RRNA

1p87, 1p6g - EcRPS19 in 30S ribosomal subunit+16S RRNA – Cryo-EM

3bbn - RPS19 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S19 in small + large ribosomal subunit
1ml5 - EcRPS19 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S19 in small ribosomal subunit+ chain release factor
3mr8, 3ms0 – TtRPS19 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA

3d5a, 3d5c - TtRPS19 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2b64 - TtRPS19 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1

2b9m - TtRPS19 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2

2x9r, 2x9t, 2wh1, 2wh3 - TtRPS19 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA

3f1e, 3f1g - TtRPS19 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA

S19 in small ribosomal subunit+tRNA+mRNA
2hgi - TtRPS19 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet

2hgp - TtRPS19 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2i2p, 2i2u - EcRPS19 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2hgr - TtRPS19 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA

1yl4 – TtRPS19 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator

1pns – EcRPS19 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA

1xnq, 1xnr - TtRPS19 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA

S19 in small ribosomal subunit+A-site tRNA
2uxd, 2uxc - TtRPS19 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA

1n32, 1n33 - TtRPS19 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA

1n34 - TtRPS19 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA

1xmo, 1xmq - TtRPS19 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA

2uxb - TtRPS19 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S19 in small ribosomal subunit+P-site tRNA
3i8g - TtRPS19 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA

3i8h, 3i9b, 3i9d - TtRPS19 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA

1ibk - TtRPS19 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA

2wwl - EcRPS19 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli

3i1q - EcRPS19 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA

3i1s, 3i1z, 3i21 - EcRPS17 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S19 in small ribosomal subunit+A-site tRNA+P-site tRNA
1ibl, 1ibm - TtRPS19 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

S19 in small ribosomal subunit+P-site tRNA+E-site tRNA
2ow8 - TtRPS19 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA

2b9o - TtRPS19 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA

2qnh - TtRPS19 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA

S19 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA
2gy9, 2gyb - EcRPS19 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM

1jgo, 1jgp, 1jgq, 1gix - TtRPS19 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA

3e1a, 3e1c - EcRPS19 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S19 in small ribosomal subunit + antibiotics
1i95, 1i97, 2hhh, 2f4v - TtRPS19 in 30S ribosomal subunit+16S RRNA+antibiotic

1hnx, 1hnw, 1hnz, 1fjg – TtRPS19 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic

2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m  - EcRPS19 in 30S ribosomal subunit+16S RRNA+antibiotic

2j00, 2j02 - TtRPS19 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA

2wdg, 2wdh, 2wdk, 2wdm - TtRPS19 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe+paromomycin

3knj, 3knh - TtRPS19 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin

3knl, 3knn - TtRPS19 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin

S19 in small ribosomal subunit + ribosome recycling factor
2qbd, 2qbf – EcRPS19 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor

3r8n, 3r8o – EcRPS19 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA

2qbh, 2qbj - EcRPS19 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

2v46, 2v48 - TtRPS19 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

S19 in small ribosomal subunit + elongation factor
2wri, 2wrk, 2xsy, 2xuy  - TtRPS19 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G

2wrn, 2wrq - TtRPS19 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4

3fic - TtRPS19 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A

3izv – EcRPS19 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU

3izw – EcRPS19 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU

2y0u, 2y0w, 2y0y, 2y12, 2y10, 2y18, 2y14, 2y16 – TtRPS19 in 30S ribosomal subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU

2xqd – TtRPS19 in 30S ribosomal subunit+THX+E-site tRNA+mRNA +16S RRNA+elongation factor TU-B

3fih - EcRPS19 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU

3huw, 3huy - Ttv in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P

1s1h - yRPS19 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast

S19 in small ribosomal subunit + translation initiation factor
1i96 - TtRPS19 in 30S ribosomal subunit+THX+IF3+16S RRNA

1hr0 - TtRPS19 in 30S ribosomal subunit+THX+IF+16S RRNA

S19 in small ribosomal subunit + various proteins
3kiq, 3kis, 3kiu, 3kix - TtRPS19 in 30S ribosomal subunit+toxin RelE+16S RRNA

1voq, 1vos, 1vov, 1vox, 1voz - EcRPS19 in 30S ribosomal subunit+protein Y+16S RRNA

2xfz, 2xg1 - TtRPS19 in 30S ribosomal subunit+tRNA Phe+mRNA+colicin E3+16S RRNA

3a1p - TtRPS19+ ribosome maturation factor RIMM

3j00 – EcRPS19 + 16S RRNA + FTSQ + apolipoprotein A-I

S19 in small 40S ribosomal subunit + various proteins
3iz6 – RPS19 in 40S ribosomal subunit+RACK1 – wheat – Cryo EM

3o2z, 3o30 – yRPS19 in 40S ribosomal subunit+18S RRNA+RACK1

3jyv - RPS19 in 40S ribosomal subunit+tRNA Phe+RACK1+18S RRNA – EM – Thermomyces lanuginosus